Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 6/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 5/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418814 | 0.90 | OXER1 (0.41) | SLC22A12ALOX5APOXER1 | |
| SCHEMBL7425988 | 0.89 | AGTR1 (0.36) | SLC22A12ALOX5APAGTR1AGTR2OXER1 | |
| SCHEMBL7425218 | 0.89 | MEN1 (0.42) | AGTR1AGTR2 | |
| SCHEMBL7427469 | 0.89 | AGTR1 (0.40) | SLC22A12ALOX5APAGTR1AGTR2OXER1 | |
| SCHEMBL7427533 | 0.87 | ALOX5AP (0.46) | SLC22A12ALOX5AP | |
| SCHEMBL7707842 | 0.87 | ALOX5AP (0.45) | SLC22A12ALOX5AP | |
| SCHEMBL7418558 | 0.83 | SLC22A12 (0.50) | SLC22A12OXER1 | |
| SCHEMBL7420996 | 0.82 | LMNA (0.40) | ALOX5APOXER1 | |
| SCHEMBL7421489 | 0.81 | SLC22A12 (0.43) | SLC22A12AGTR1AGTR2FABP4 | |
| SCHEMBL7472730 | 0.80 | MEN1 (0.39) | ALOX5AP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358992-B1 | Method of inhibiting neoplastic cells with indole derivatives | CELL PATHWAYS, INC. | 2002-03-19 | — | — | US | disclosed |