Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 4/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8357807 | 0.83 | CYP2C9 (0.43) | ALDH1A1MAPTHTR1AHTR7TSHR | |
| SCHEMBL7881075 | 0.83 | SLC6A4 (0.43) | SLC6A4HTR1AGPR84HTR2A | |
| SCHEMBL5240727 | 0.80 | BCHE (0.42) | SLC6A4HTR1AHTR2A | |
| SCHEMBL27397651 | 0.78 | KDR (0.63) | ALDH1A1MAPTSLC6A4MPOHTR1A | |
| SCHEMBL9377656 | 0.74 | HTR6 (0.39) | MAPTGPR84HTR2A | |
| SCHEMBL7887655 | 0.74 | ALDH1A1 (0.41) | ALDH1A1MAPTHTR2C | |
| SCHEMBL9374925 | 0.72 | GABRP (0.36) | — | |
| SCHEMBL9696184 | 0.71 | HTR2A (0.43) | ALDH1A1GPR84HTR2A | |
| SCHEMBL9376538 | 0.70 | PSMD14 (0.41) | SLC6A4HTR1ATSHRHTR2AHTR2C | |
| SCHEMBL9376902 | 0.69 | GABRP (0.40) | MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200072-A2 | METHOD OF TREATING PSYCHOTIC DISORDERS | Solvay Pharmaceuticals B.V. (NL) | 2002-05-02 | — | — | EP | disclosed |
| WO-2000069424-A2 | METHOD OF TREATING PSYCHOTIC DISORDERS | SOLVAY PHARMACEUTICALS B.V. (NL) | 2000-11-23 | — | — | WO | disclosed |