Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3379193 | 0.81 | LMNA (0.52) | KDM4EFBP1MAPTKMT2APOLB | |
| SCHEMBL8429265 | 0.79 | SMN1; SMN2 (0.45) | KDM4EFBP1MAPTALDH1A1CYP3A4 | |
| SCHEMBL872573 | 0.78 | FBP1 (0.49) | KDM4EFBP1MAPTKMT2APOLB | |
| SCHEMBL15156883 | 0.78 | FBP1 (0.49) | KDM4EFBP1MAPTKMT2APOLB | |
| SCHEMBL4764865 | 0.78 | HPGD (0.51) | KDM4EFBP1MAPTKMT2APOLB | |
| SCHEMBL1787731 | 0.78 | ALDH1A1 (0.52) | KDM4EMAPTALDH1A1SMN1; SMN2HSP90AA1 | |
| SCHEMBL1308132 | 0.77 | TUBB4A (0.49) | KDM4EMAPT | |
| SCHEMBL7470078 | 0.76 | MAPT (0.46) | MAPTCYP3A4BLMPMP22 | |
| SCHEMBL1275821 | 0.76 | MAPT (0.64) | MAPTKMT2APOLBALDH1A1MEN1 | |
| SCHEMBL12312090 | 0.75 | ALDH1A1 (0.56) | KDM4EFBP1MAPTKMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0691967-B1 | NITROGEN-CONTAINING FUSED-HETEROCYCLE COMPOUNDS | EISAI CO LTD (JP) | 1998-09-02 | — | — | EP | disclosed |
| US-5707998-A | CYCLIC-GMP PHOSPHODIESTERASE INHIBITORS, TREATING CARDIOVASCULAR DISORDERS AND ASTHMA | EISAI CO., LTD. (JP) | 1998-01-13 | — | — | US | disclosed |
| WO-1994022855-A1 | NITROGEN-CONTAINING FUSED-HETEROCYCLE COMPOUNDS | EISAI CO., LTD. (JP) | 1994-10-13 | — | — | WO | disclosed |