Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 20/20 | 0.45 |
| ▸ | CASP6 | P55212 | 19/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 19/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6831408 | 0.89 | CASP3 (0.50) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL6831425 | 0.80 | CTSV (0.45) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL7200874 | 0.70 | CASP3 (0.40) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL7201965 | 0.69 | CASP3 (0.77) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL26616368 | 0.66 | CYP1A2 (0.58) | — | |
| SCHEMBL26616374 | 0.66 | CYP1A2 (0.58) | — | |
| SCHEMBL7404706 | 0.66 | CASP3 (0.57) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL8258564 | 0.66 | CYP1A2 (0.61) | — | |
| SCHEMBL25985226 | 0.66 | KDM4E (0.52) | CASP3CASP6CASP8CASP7 | |
| SCHEMBL6830923 | 0.64 | LMNA (0.42) | CASP3CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020091089-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | KARANEWSKY DONALD S (US) | 2002-07-11 | — | — | US | disclosed |
| EP-1123272-A1 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/CED-3 FAMILY OF CYSTEINE PROTEASES | Idun Pharmaceuticals, Inc. (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000023421-A1 | (SUBSTITUTED)ACYL DIPEPTIDYL INHIBITORS OF THE ICE/ced-3 FAMILY OF CYSTEINE PROTEASES | IDUN PHARMACEUTICALS, INC. (US) | 2000-04-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020091089-A1 | (Substituted)acyl dipeptidyl inhibitors of the ICE/ced-3 family of cysteine proteases | DPP3, IAPP, CASP3 | CASP3 3/4885CASP6 26/4885CASP8 38/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.