Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420833 | 0.75 | L3MBTL1 (0.41) | EPHX1 | |
| SCHEMBL6371524 | 0.71 | L3MBTL1 (0.40) | EPHX1 | |
| Hydrochloric Acid SCHEMBL7418337 | 0.70 | CTSS (0.40) | EPHX1 | |
| SCHEMBL7013068 | 0.67 | CTSS (0.48) | EPHX1 | |
| SCHEMBL7014390 | 0.65 | L3MBTL1 (0.43) | EPHX1 | |
| SCHEMBL7412211 | 0.65 | CTSK (0.32) | — | |
| SCHEMBL5927948 | 0.63 | EPHX1 (0.65) | EPHX1 | |
| SCHEMBL5927952 | 0.63 | EPHX1 (0.65) | EPHX1 | |
| SCHEMBL8296553 | 0.63 | DPP4 (0.40) | — | |
| SCHEMBL14311888 | 0.62 | CPN1 (0.40) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218372-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | Boehringer Ingelheim Pharmaceuticals, Inc. (US) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001019816-A1 | NOVEL SPIROHETEROCYCLIC COMPOUNDS USEFUL AS REVERSIBLE INHIBITORS OF CYSTEINE PROTEASES | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-03-22 | — | — | WO | disclosed |