SCHEMBL7419927

SCHEMBL7419927

C[C@@H](C(=O)S)N(C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.41
LMNA P02545 1/20 0.41
TP53 P04637 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
NPSR1 Q6W5P4 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
HTT P42858 1/20 0.39
SLC6A2 P23975 3/20 0.39
SLC6A4 P31645 3/20 0.39
GLA P06280 1/20 0.38
TSHR P16473 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
CHRNA4 P43681 1/20 0.38
PGR P06401 1/20 0.38
ADRA2A P08913 1/20 0.38
ADRA2B P18089 1/20 0.38
HTR2A P28223 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL755702 0.83 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL755703 0.83 ALDH1A1 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL8226909 0.82 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL32662705 0.82 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2NPSR1
Hydrochloric Acid SCHEMBL8226911 0.82 ALDH1A1 (0.42) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL8586520 0.80 ALOX5 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL1821413 0.80 ALOX5 (0.43) ALDH1A1LMNATP53SMN1; SMN2NPSR1
SCHEMBL1822378 0.78 KMT2A (0.44) LMNASMN1; SMN2KMT2AHTTCHRNB2
SCHEMBL9191050 0.77 KMT2A (0.48) NPSR1KMT2AMEN1HTTTSHR
SCHEMBL6495233 0.74 PIN1 (0.47) ALDH1A1LMNATP53SMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0287605-A1 AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) 1988-10-26 EP disclosed
WO-1988002363-A1 AMINO-2 ETHANETHIOL DERIVATIVES, PREPARATION AND THERAPEUTIC APPLICATION THEREOF INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE M (FR) 1988-04-07 WO disclosed