Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 7/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422232 | 0.92 | THRB (0.46) | ITGB1ITGA4KMT2AMEN1L3MBTL1 | |
| SCHEMBL7423048 | 0.90 | ITGB1 (0.44) | ITGB1ITGA4KMT2AMEN1LMNA | |
| SCHEMBL7420801 | 0.89 | ITGB1 (0.47) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7428920 | 0.86 | ITGB1 (0.47) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7425039 | 0.84 | ITGB1 (0.54) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7431414 | 0.83 | ACHE (0.54) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7390416 | 0.82 | ITGA4 (0.52) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7387094 | 0.82 | ITGB1 (0.54) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7426841 | 0.81 | ITGA4 (0.51) | ITGB1ITGA4KMT2AMEN1MAPT | |
| SCHEMBL7425047 | 0.80 | ITGB1 (0.54) | ITGB1ITGA4KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999054321-A1 | SUBSTITUTED DIAMINES AND THEIR USE AS CELL ADHESION INHIBITORS | AVENTIS PHARMA LIMITED (GB) | 1999-10-28 | — | — | WO | disclosed |