Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 12/20 | 0.78 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.64 |
| ▸ | PDE4A | P27815 | 2/20 | 0.64 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.64 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | PTGES | O14684 | 1/20 | 0.60 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.60 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.59 |
| ▸ | MEP1A | Q16819 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7413611 | 0.91 | TAS2R14 (0.68) | TAS2R14MEP1BPDE4APDE4BPDE4C | |
| SCHEMBL7422229 | 0.91 | TAS2R14 (0.89) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7417394 | 0.88 | PDE4A (0.79) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1279106 | 0.87 | TAS2R14 (1.00) | TAS2R14PTGESTAS2R8CXCR3MEN1 | |
| SCHEMBL7428277 | 0.86 | TAS2R14 (0.67) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7416090 | 0.84 | TAS2R14 (0.74) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7423414 | 0.84 | PDE4A (0.67) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7422978 | 0.83 | TAS2R14 (0.69) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL1615782 | 0.83 | TAS2R14 (0.83) | TAS2R14MEP1BPTGESCXCR3MEN1 | |
| SCHEMBL7419343 | 0.82 | HSD11B1 (0.65) | TAS2R14PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |