Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 17/20 | 0.89 |
| ▸ | PTGES | O14684 | 1/20 | 0.72 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.72 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.72 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PDE4A | P27815 | 2/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1279106 | 0.94 | TAS2R14 (1.00) | TAS2R14PTGESTAS2R8CXCR3MEN1 | |
| SCHEMBL7420151 | 0.91 | TAS2R14 (0.78) | TAS2R14PTGESTAS2R8CXCR3MEN1 | |
| SCHEMBL7416090 | 0.91 | TAS2R14 (0.74) | TAS2R14PTGESTAS2R8CXCR3PDE4A | |
| SCHEMBL7417394 | 0.90 | PDE4A (0.79) | TAS2R14PTGESTAS2R8CXCR3PDE4A | |
| SCHEMBL7418883 | 0.88 | PDE4A (0.78) | TAS2R14PTGESTAS2R8CXCR3MEN1 | |
| SCHEMBL7422978 | 0.88 | TAS2R14 (0.69) | TAS2R14PTGESTAS2R8CXCR3PDE4A | |
| SCHEMBL1279785 | 0.87 | TAS2R14 (1.00) | TAS2R14PTGESTAS2R8CXCR3MEN1 | |
| SCHEMBL1279152 | 0.86 | TAS2R14 (1.00) | TAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL7418318 | 0.85 | PDE4A (0.69) | TAS2R14PTGESTAS2R8CXCR3MEN1 | |
| SCHEMBL7413611 | 0.84 | TAS2R14 (0.68) | TAS2R14PTGESTAS2R8CXCR3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |