Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R14 | Q9NYV8 | 13/20 | 0.67 |
| ▸ | PDE4A | P27815 | 3/20 | 0.67 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.67 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.50 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.50 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422978 | 0.90 | TAS2R14 (0.69) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7417394 | 0.90 | PDE4A (0.79) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7420151 | 0.86 | TAS2R14 (0.78) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7423414 | 0.86 | PDE4A (0.67) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7413611 | 0.84 | TAS2R14 (0.68) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7422229 | 0.83 | TAS2R14 (0.89) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7418318 | 0.83 | PDE4A (0.69) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7423955 | 0.83 | PDE4A (0.63) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7425269 | 0.83 | PDE4A (0.63) | TAS2R14PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7422201 | 0.81 | PDE4A (0.67) | TAS2R14PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | claimed |
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | disclosed |