Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.60 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.60 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.57 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.57 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.54 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 3/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL126452 | 0.87 | LMNA (0.70) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| SCHEMBL1746578 | 0.82 | LTA4H (0.71) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| SCHEMBL6192316 | 0.82 | LMNA (0.63) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| Trifluoroacetic Acid SCHEMBL8208389 | 0.81 | PTPN1 (0.63) | FFAR1FFAR4PTGS1LTA4HPPARG | |
| SCHEMBL2381708 | 0.81 | CES1 (0.69) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| SCHEMBL7420439 | 0.81 | MAOB (0.58) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| Trifluoroacetic Acid SCHEMBL17136548 | 0.81 | MAOB (0.63) | FFAR1FFAR4MAOBPPARG | |
| SCHEMBL5400014 | 0.81 | APP (0.64) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| SCHEMBL7764407 | 0.79 | NR4A2 (0.68) | FFAR1FFAR4NR4A1NR4A2NR4A3 | |
| SCHEMBL3490381 | 0.79 | FFAR1 (0.70) | FFAR1FFAR4LTA4HEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021411-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 2000-07-26 | — | — | EP | disclosed |
| WO-1997022589-A1 | BENZAMIDE DERIVATIVES AS THROMBIN INHIBITORS | GLAXO GROUP LIMITED (GB) | 1997-06-26 | — | — | WO | disclosed |