Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 4/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7426509 | 0.81 | MMP3 (0.39) | KDM4EALDH1A1APOBEC3GMMP3GAA | |
| SCHEMBL7360658 | 0.76 | KMT2A (0.34) | KDM4EALDH1A1APOBEC3GHPGDMMP3 | |
| SCHEMBL11299252 | 0.70 | LARS1 (0.39) | — | |
| SCHEMBL8693203 | 0.66 | SLC7A5 (0.36) | — | |
| SCHEMBL10953721 | 0.64 | SLC7A5 (0.41) | — | |
| SCHEMBL28195149 | 0.64 | SLC7A5 (0.41) | — | |
| SCHEMBL11473563 | 0.64 | MCL1 (0.41) | KDM4EALDH1A1HPGDCA1CA2 | |
| SCHEMBL8773630 | 0.63 | SLC7A5 (0.36) | — | |
| SCHEMBL7349668 | 0.63 | GRIK1 (0.35) | — | |
| SCHEMBL28916811 | 0.62 | SLC7A5 (0.35) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |