Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 14/20 | 0.39 |
| ▸ | MMP1 | P03956 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | GLS | O94925 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420570 | 0.81 | KDM4E (0.34) | MMP3KDM4EALDH1A1GAAAPOBEC3G | |
| SCHEMBL7426285 | 0.77 | MMP3 (0.44) | MMP3MMP1ALDH1A1MMP2SLC7A5 | |
| SCHEMBL7358708 | 0.74 | MMP3 (0.42) | MMP3MMP1MMP2 | |
| SCHEMBL7357685 | 0.70 | MMP3 (0.44) | MMP3MMP1ALDH1A1MMP2 | |
| SCHEMBL2307682 | 0.69 | LTA4H (0.55) | MMP3MMP1CTSSCTSKSLC7A5 | |
| SCHEMBL2307679 | 0.69 | LTA4H (0.55) | MMP3MMP1CTSSCTSKSLC7A5 | |
| SCHEMBL27878054 | 0.69 | LTA4H (0.55) | MMP3MMP1CTSSCTSKSLC7A5 | |
| SCHEMBL7361335 | 0.69 | MMP3 (0.42) | MMP3MMP1ALDH1A1CTSSCTSK | |
| SCHEMBL7364809 | 0.69 | MMP3 (0.39) | MMP3MMP1ALDH1A1CTSSCTSK | |
| Hydrochloric Acid SCHEMBL29264506 | 0.68 | LTA4H (0.54) | MMP3MMP1CTSSCTSKSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998025949-A1 | SUBSTITUTED 5-AMINO-1,3,4-THIADIAZOLE-2-THIONES | PROSCRIPT, INC. (US) | 1998-06-18 | — | — | WO | disclosed |