Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.41 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 7/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 7/20 | 0.38 |
| ▸ | KCNE1 | P15382 | 4/20 | 0.38 |
| ▸ | KCNQ1 | P51787 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.36 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.36 |
| ▸ | GRN | P28799 | 1/20 | 0.36 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7427045 | 0.85 | GRIA2 (0.52) | ALDH1A1RAB9AGRIA2NPC1GRN | |
| SCHEMBL7426474 | 0.85 | GRIA2 (0.52) | ALDH1A1RAB9AGRIA2NPC1GRN | |
| SCHEMBL7419434 | 0.82 | ALDH1A1 (0.54) | ALDH1A1RAB9AKCNQ3KCNQ2NPC1 | |
| SCHEMBL8256279 | 0.78 | RAB9A (0.42) | ALDH1A1RAB9AGRIA2P4HTMKCNQ3 | |
| SCHEMBL5869809 | 0.78 | RAB9A (0.42) | ALDH1A1RAB9AGRIA2P4HTMKCNQ3 | |
| SCHEMBL5869763 | 0.72 | FOLH1 (0.48) | RAB9AGRIA2NPC1GRNSORT1 | |
| SCHEMBL5869867 | 0.72 | FOLH1 (0.48) | RAB9AGRIA2NPC1GRNSORT1 | |
| SCHEMBL5869771 | 0.72 | FOLH1 (0.48) | RAB9AGRIA2NPC1GRNSORT1 | |
| SCHEMBL7377704 | 0.70 | GRN (0.43) | ALDH1A1KDM4EGRNSORT1SMN1; SMN2 | |
| SCHEMBL7420625 | 0.69 | ALDH1A1 (0.40) | ALDH1A1RAB9AGRIA2P4HTMKCNQ3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002039997-A2 | ACE-2 MODULATING COMPOUNDS AND USE THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-05-23 | — | — | WO | disclosed |