Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SERPINH1 | P50454 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7408562 | 0.83 | KDM4E (0.37) | KDM4EALDH1A1HTTATM | |
| SCHEMBL12035513 | 0.82 | PKM (0.47) | ALDH1A1 | |
| SCHEMBL2465219 | 0.82 | AKR1C4 (0.38) | KDM4EALDH1A1HTTATM | |
| SCHEMBL7419268 | 0.78 | ALDH1A1 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL671175 | 0.77 | MEN1 (0.38) | MEN1KMT2AKDM4EALDH1A1SERPINH1 | |
| SCHEMBL7416197 | 0.76 | HTR3A (0.35) | — | |
| SCHEMBL7417950 | 0.73 | HTR3A (0.48) | MEN1KMT2A | |
| SCHEMBL16742340 | 0.72 | PKM (0.37) | KDM4EALDH1A1PDK2HTT | |
| SCHEMBL8366432 | 0.71 | HTR3A (0.43) | MEN1KMT2AKDM4EALDH1A1SERPINH1 | |
| SCHEMBL14818339 | 0.71 | FFAR4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1991016888-A1 | SPIRO[BENZOFURANCYCLOALKANE]CARBOXAMIDES AS 5HT3 ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1991-11-14 | — | — | WO | disclosed |