Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | DRD4 | P21917 | 3/20 | 0.61 |
| ▸ | DRD2 | P14416 | 2/20 | 0.60 |
| ▸ | DRD3 | P35462 | 2/20 | 0.60 |
| ▸ | SMO | Q99835 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.58 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6412144 | 0.87 | KDM4E (1.00) | LMNAKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL6412440 | 0.84 | KDM4E (0.72) | LMNAKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL12856255 | 0.82 | KMT2A (0.76) | LMNAKDM4EKMT2AALDH1A1CYP2A13 | |
| SCHEMBL24403536 | 0.80 | KMT2A (1.00) | LMNAKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL11891934 | 0.80 | KMT2A (0.73) | LMNAKDM4EKMT2AALDH1A1CYP2A13 | |
| SCHEMBL329437 | 0.80 | KMT2A (0.72) | LMNAKDM4EKMT2AALDH1A1CYP2A13 | |
| SCHEMBL8162127 | 0.79 | KDM4E (0.66) | LMNAKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL7424306 | 0.79 | HTR7 (0.69) | LMNAKDM4EKMT2AALDH1A1HTT | |
| SCHEMBL4108854 | 0.79 | CYP2A13 (1.00) | LMNAKDM4EKMT2AALDH1A1CYP2A13 | |
| SCHEMBL1882777 | 0.78 | KMT2A (0.70) | LMNAKDM4EKMT2AALDH1A1CYP2A13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998008091-A1 | NORMALIZATION OF COMBINATORIAL REACTIONS | ISIS PHARMACEUTICALS, INC. (US) | 1998-02-26 | — | — | WO | disclosed |
| WO-1997044334-A2 | NOVEL PIPERAZINE OR HOMOPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THEIR PREPARATION | EGIS Gyógyszergyár Rt. (HU) | 1997-11-27 | — | — | WO | disclosed |