Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | HTT | P42858 | 1/20 | 0.66 |
| ▸ | DRD4 | P21917 | 4/20 | 0.61 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.57 |
| ▸ | DRD3 | P35462 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856323 | 0.82 | MPO (0.57) | HTR7KDM4EALDH1A1HTTLMNA | |
| SCHEMBL29764254 | 0.81 | HTR7 (1.00) | HTR7KDM4EALDH1A1HTTDRD4 | |
| SCHEMBL15938148 | 0.81 | HTR7 (1.00) | HTR7KDM4EALDH1A1HTTDRD4 | |
| SCHEMBL28627893 | 0.80 | VEGFA (0.61) | KDM4EALDH1A1HTTLMNASMN1; SMN2 | |
| SCHEMBL8162127 | 0.79 | KDM4E (0.66) | HTR7KDM4EALDH1A1HTTDRD4 | |
| SCHEMBL7420674 | 0.79 | LMNA (0.77) | HTR7KDM4EALDH1A1HTTDRD4 | |
| SCHEMBL3242189 | 0.79 | DRD4 (0.77) | HTR7KDM4EALDH1A1HTTDRD4 | |
| SCHEMBL7479293 | 0.79 | ALDH1A1 (0.60) | HTR7KDM4EALDH1A1HTTDRD4 | |
| SCHEMBL17982842 | 0.79 | MC4R (0.56) | KDM4EALDH1A1DRD4DRD3SMN1; SMN2 | |
| SCHEMBL2251851 | 0.79 | CYP2A13 (0.64) | KDM4EALDH1A1HTTLMNAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044334-A2 | NOVEL PIPERAZINE OR HOMOPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THEIR PREPARATION | EGIS Gyógyszergyár Rt. (HU) | 1997-11-27 | — | — | WO | disclosed |