Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | FPR2 | P25090 | 10/20 | 0.49 |
| ▸ | FPR1 | P21462 | 7/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | USP14 | P54578 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420917 | 1.00 | ITGB3 (0.49) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| Trifluoroacetic Acid SCHEMBL8121463 | 0.95 | FPR2 (0.46) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL8117283 | 0.86 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL8117290 | 0.86 | ITGB3 (0.68) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL8117293 | 0.86 | ITGB3 (0.50) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| Trifluoroacetic Acid SCHEMBL7422390 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| Trifluoroacetic Acid SCHEMBL7422393 | 0.81 | ITGB3 (0.46) | ITGB3ITGA2BFPR2FPR1NPY1R | |
| SCHEMBL7420718 | 0.81 | ITGB3 (0.72) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL7415603 | 0.81 | ITGB3 (0.72) | ITGB3ITGA2BFPR2FPR1HDAC1 | |
| SCHEMBL27368967 | 0.80 | ITGB3 (0.65) | ITGB3ITGA2BFPR2FPR1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994022820-A1 | 1-AMIDINOPHENYL-PYRROLIDONES PIPERIDINONES AZETINONES AS PLATELET AGGREGATION INHIBITORS | G.D. SEARLE & CO. (US) | 1994-10-13 | — | — | WO | disclosed |