Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 2/20 | 0.78 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.78 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.78 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.78 |
| ▸ | TAS2R14 | Q9NYV8 | 14/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA2 | P00918 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.59 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.59 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.59 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.59 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.59 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.59 |
| ▸ | PTGES | O14684 | 1/20 | 0.57 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418683 | 0.90 | PDE4A (0.80) | PDE4APDE4BPDE4CPDE4DTAS2R14 | |
| SCHEMBL7422229 | 0.88 | TAS2R14 (0.89) | PDE4APDE4BPDE4CPDE4DTAS2R14 | |
| SCHEMBL1279042 | 0.85 | TAS2R14 (1.00) | TAS2R14CA12CA2RAB9ASMN1; SMN2 | |
| SCHEMBL1279106 | 0.83 | TAS2R14 (1.00) | TAS2R14MEN1KMT2APTGESTAS2R8 | |
| SCHEMBL1279152 | 0.82 | TAS2R14 (1.00) | TAS2R14PTGESTAS2R8CXCR3 | |
| SCHEMBL7206100 | 0.81 | L3MBTL1 (0.76) | PDE4APDE4BPDE4CPDE4DCA12 | |
| SCHEMBL7421609 | 0.80 | PDE4D (0.63) | PDE4APDE4BPDE4CPDE4DTAS2R14 | |
| SCHEMBL7418172 | 0.80 | PDE4A (0.66) | PDE4APDE4BPDE4CPDE4DTAS2R14 | |
| SCHEMBL7416090 | 0.80 | TAS2R14 (0.74) | PDE4APDE4BPDE4CPDE4DTAS2R14 | |
| SCHEMBL7420151 | 0.80 | TAS2R14 (0.78) | PDE4APDE4BPDE4CPDE4DTAS2R14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996036595-A1 | 3,4-DISUBSTITUTED-PHENYLSULPHONAMIDES AND THEIR THERAPEUTIC USE | CHIROSCIENCE LIMITED (GB) | 1996-11-21 | — | — | WO | claimed |