Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.33 |
| ▸ | PARP1 | P09874 | 4/20 | 0.32 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9319857 | 0.85 | MAOA (0.38) | MAOAMAOBNOTUMHSD17B3ALOX5 | |
| SCHEMBL29569443 | 0.81 | MAOA (0.41) | MAOAMAOBATMNOTUMTRPA1 | |
| SCHEMBL2971412 | 0.81 | MAOA (0.41) | MAOAMAOBATMNOTUMTRPA1 | |
| Hydrochloric Acid SCHEMBL19744197 | 0.80 | MAOA (0.39) | MAOAMAOBATMNOTUMTRPA1 | |
| SCHEMBL11551370 | 0.79 | MAOA (0.38) | MAOAMAOB | |
| SCHEMBL11556597 | 0.76 | MAOA (0.42) | MAOAMAOBATM | |
| Trifluoroacetic Acid SCHEMBL29570875 | 0.73 | MAOA (0.33) | MAOAMAOBATMNOTUMTRPA1 | |
| SCHEMBL5848189 | 0.73 | TRPA1 (0.41) | ATMTRPA1PARP1 | |
| SCHEMBL9259332 | 0.71 | MAOA (0.41) | MAOAMAOBATM | |
| Acetamide SCHEMBL7696552 | 0.70 | SMN1; SMN2 (0.38) | MAOAMAOBATMNOTUMPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5288731-A | Antiemetics, antiserotonine agents | RHONE-POULENC RORER PHARMACEUTICALS INC. (US) | 1994-02-22 | — | — | US | disclosed |
| WO-1992009284-A1 | 2,6-METHANO-2H-1-BENZOXOCINCARBOXAMIDES AS 5-HT3-ANTAGONISTS | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS), INC. (US) | 1992-06-11 | — | — | WO | disclosed |