Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.67 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.67 |
| ▸ | REN | P00797 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPY1R | P25929 | 2/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL739843 | 0.97 | HRH1 (0.70) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL739842 | 0.97 | HRH1 (0.70) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL763158 | 0.85 | HRH1 (0.68) | HRH1CHRM1OPRM1OPRD1OPRK1 | |
| SCHEMBL741971 | 0.84 | HRH1 (0.53) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL740713 | 0.84 | HRH1 (0.53) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL741972 | 0.84 | HRH1 (0.53) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL740712 | 0.84 | HRH1 (0.53) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL742774 | 0.83 | HRH1 (0.54) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL740756 | 0.83 | HRH1 (0.52) | HRH1CHRM1RENOPRM1OPRD1 | |
| SCHEMBL742773 | 0.83 | HRH1 (0.54) | HRH1CHRM1RENOPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138168-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-20 | — | — | US | disclosed |