Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GPR183 | P32249 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422143 | 0.95 | MAPT (0.53) | GPR183MAPTMEN1KMT2AATM | |
| SCHEMBL7425120 | 0.85 | SIGMAR1 (0.64) | ALDH1A1 | |
| SCHEMBL26962967 | 0.84 | HRH3 (0.67) | ALDH1A1MAPTHRH3MCHR1KDM4E | |
| Hydrochloric Acid SCHEMBL23850153 | 0.82 | HRH3 (0.64) | ALDH1A1MAPTHRH3MCHR1KDM4E | |
| SCHEMBL7425525 | 0.82 | ALDH1A1 (0.68) | ALDH1A1GPR183MEN1KMT2AFAAH | |
| SCHEMBL511084 | 0.81 | CCR2 (0.56) | ALDH1A1HRH3MEN1KMT2AKDM4E | |
| SCHEMBL5319459 | 0.80 | HRH3 (0.74) | ALDH1A1MAPTHRH3MCHR1KDM4E | |
| SCHEMBL8117468 | 0.80 | MAPT (0.67) | MAPK1MAPTHRH3KDM4E | |
| SCHEMBL7424630 | 0.80 | SIGMAR1 (0.65) | HRH3 | |
| SCHEMBL7421573 | 0.80 | SIGMAR1 (0.67) | ALDH1A1GPR183MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997044334-A2 | NOVEL PIPERAZINE OR HOMOPIPERAZINE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND A PROCESS FOR THEIR PREPARATION | EGIS Gyógyszergyár Rt. (HU) | 1997-11-27 | — | — | WO | disclosed |