Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 10/20 | 0.55 |
| ▸ | MMP13 | P45452 | 10/20 | 0.55 |
| ▸ | MMP9 | P14780 | 9/20 | 0.55 |
| ▸ | ADAM17 | P78536 | 6/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 8/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 8/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6289470 | 0.92 | MMP1 (0.53) | MMP1MMP13MMP9ADAM17TP53 | |
| SCHEMBL7012429 | 0.92 | MMP1 (0.68) | MMP1MMP13MMP9ADAM17 | |
| SCHEMBL6293228 | 0.88 | MMP1 (0.49) | MMP1MMP13MMP9ADAM17KEAP1 | |
| SCHEMBL7004527 | 0.85 | MMP1 (0.51) | MMP1MMP13MMP9ADAM17KEAP1 | |
| SCHEMBL6289453 | 0.82 | MAPT (0.51) | MMP1MMP13MMP9ADAM17KEAP1 | |
| SCHEMBL6290010 | 0.79 | MMP1 (0.85) | MMP1MMP13MMP9ADAM17 | |
| SCHEMBL6290541 | 0.76 | MMP13 (0.85) | MMP1MMP13MMP9ADAM17 | |
| SCHEMBL6290574 | 0.76 | MMP1 (0.67) | MMP1MMP13MMP9ADAM17 | |
| SCHEMBL6290086 | 0.75 | MMP1 (0.66) | MMP1MMP13MMP9ADAM17KEAP1 | |
| Hydroxyamine SCHEMBL7418152 | 0.75 | MMP13 (0.82) | MMP1MMP13MMP9ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1998016514-A1 | ORTHO-SULFONAMIDO BICYCLIC HETEROARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1998-04-23 | — | — | WO | disclosed |