Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PREP | P48147 | 2/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7045087 | 0.85 | NPC1 (0.61) | NPC1RAB9AL3MBTL1NOTUMPTGER1 | |
| SCHEMBL7423680 | 0.82 | L3MBTL1 (0.52) | NPC1RAB9AL3MBTL1NOTUMPTGER1 | |
| SCHEMBL10832646 | 0.78 | PREP (0.47) | NPC1RAB9AL3MBTL1POLBCA12 | |
| SCHEMBL9377728 | 0.76 | LIPE (0.51) | NPC1RAB9AL3MBTL1POLBCA12 | |
| SCHEMBL7379822 | 0.76 | CASP1 (0.52) | NPC1RAB9AL3MBTL1POLBCA12 | |
| SCHEMBL12474901 | 0.73 | NPC1 (0.63) | NPC1RAB9AL3MBTL1NOTUMPOLB | |
| SCHEMBL5647759 | 0.72 | LIPE (0.49) | NPC1RAB9AL3MBTL1POLBCA12 | |
| SCHEMBL876242 | 0.72 | CASP1 (0.48) | NPC1RAB9APOLBCA12CA1 | |
| SCHEMBL9201957 | 0.72 | POLB (0.51) | NPC1RAB9AL3MBTL1NOTUMPTGER1 | |
| SCHEMBL15201849 | 0.70 | F10 (0.56) | CA12CA1CA2CA9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4210967-A | — | — | None | — | — | JP | disclosed |
| JP-H04210967-A | 2-BENZAZEPINE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1992-08-03 | — | — | JP | disclosed |