Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ASPH | Q12797 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | RBP4 | P02753 | 1/20 | 0.36 |
| ▸ | CDK8 | P49336 | 1/20 | 0.36 |
| ▸ | CDK19 | Q9BWU1 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27077029 | 1.00 | ALOX15 (0.41) | ALOX15TSHRHIF1AP2RX7ALDH1A1 | |
| SCHEMBL22695513 | 0.85 | LMNA (0.42) | P2RX7ALDH1A1HSP90AA1HSP90AB1HSD17B10 | |
| SCHEMBL29882592 | 0.84 | HSP90AA1 (0.42) | P2RX7ALDH1A1HSP90AA1HSP90AB1HSD17B10 | |
| SCHEMBL18839634 | 0.84 | HSP90AA1 (0.42) | P2RX7ALDH1A1HSP90AA1HSP90AB1HSD17B10 | |
| SCHEMBL4086004 | 0.82 | ALOX15 (0.35) | ALOX15TSHRHIF1AASPHIGFBP3 | |
| SCHEMBL22540919 | 0.81 | P2RX7 (0.59) | P2RX7ALDH1A1HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL2342015 | 0.80 | NQO2 (0.46) | P2RX7ALDH1A1HSP90AA1HSP90AB1KDM4E | |
| SCHEMBL745813 | 0.80 | TSHR (0.61) | ALOX15TSHRHIF1AALDH1A1ASPH | |
| SCHEMBL742374 | 0.80 | TSHR (0.61) | ALOX15TSHRHIF1AALDH1A1ASPH | |
| SCHEMBL12097960 | 0.79 | CES2 (0.45) | ALOX15TSHRHIF1AP2RX7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117098764-A | Tetrahydrothienopyridine derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-11-21 | — | — | CN | disclosed |
| CN-117062812-A | Indoline derivatives as DDR inhibitors | 奇斯药制品公司 | 2023-11-14 | — | — | CN | disclosed |