Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 6/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MME | P08473 | 1/20 | 0.40 |
| ▸ | ACE | P12821 | 1/20 | 0.40 |
| ▸ | CPA1 | P15085 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PGA5 | P0DJD9 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7418157 | 0.96 | REN (0.45) | RENCASP3CASP7CTSDELANE | |
| SCHEMBL7421382 | 0.94 | REN (0.42) | RENCASP3CASP7CTSDELANE | |
| SCHEMBL7415239 | 0.93 | REN (0.41) | RENCTSDELANEPGA5 | |
| SCHEMBL8945566 | 0.91 | CTSD (0.47) | RENCASP3CASP7CTSDMME | |
| SCHEMBL7933938 | 0.91 | CTSD (0.47) | RENCASP3CASP7CTSDMME | |
| SCHEMBL7421246 | 0.88 | GPR132 (0.44) | RENCTSDELANE | |
| SCHEMBL7417968 | 0.88 | GPR132 (0.44) | RENCTSDELANE | |
| SCHEMBL8054257 | 0.86 | CTSD (0.48) | RENCASP3CASP7CTSDCA2 | |
| SCHEMBL7418725 | 0.86 | MME (0.46) | MMEACECPA1ACE2MAOB | |
| SCHEMBL8364492 | 0.85 | CTSD (0.48) | RENCASP3CASP7CTSDELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | claimed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |