Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.47 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | CMA1 | P23946 | 3/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7933938 | 1.00 | CTSD (0.47) | CTSDITGB3ITGA2BMMEACE | |
| SCHEMBL7417968 | 0.94 | GPR132 (0.44) | CTSDCTSKCTSSRENCTSB | |
| SCHEMBL7421246 | 0.94 | GPR132 (0.44) | CTSDCTSKCTSSRENCTSB | |
| SCHEMBL7422223 | 0.93 | ITGB3 (0.45) | CTSDITGB3ITGA2BMMEACE | |
| SCHEMBL7418725 | 0.93 | MME (0.46) | MMEACECPA1ACE2 | |
| SCHEMBL7421155 | 0.92 | CTSD (0.43) | CTSDITGB3ITGA2BMMEACE | |
| SCHEMBL7422846 | 0.92 | CTSD (0.44) | CTSDITGB3ITGA2BMMEACE | |
| SCHEMBL7423864 | 0.91 | REN (0.45) | CTSDITGB3ITGA2BMMEACE | |
| SCHEMBL7425178 | 0.89 | GPR132 (0.44) | CTSDITGB3ITGA2BCTSKCTSS | |
| SCHEMBL8041651 | 0.89 | MME (0.47) | CTSDITGB3ITGA2BMMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5559140-A | VIRICIDES | MERRELL PHARMACEUTICALS INC. (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0565631-B1 | ANTI-VIRAL COMPOUNDS | MERRELL PHARMA INC (US) | 1996-09-18 | — | — | EP | disclosed |
| EP-0565631-A1 | ANTI-VIRAL COMPOUNDS. | MERRELL DOW PHARMA (US) | 1993-10-20 | — | — | EP | disclosed |
| WO-1992012123-A1 | ANTI-VIRAL COMPOUNDS | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-07-23 | — | — | WO | disclosed |