Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GRK2 | P25098 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 5/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.32 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30089883 | 0.76 | AHR (0.41) | MAPTALPLALDH1A1MEN1KMT2A | |
| SCHEMBL6454308 | 0.73 | IDO1 (0.57) | MAPTALDH1A1NPSR1IDO1MEN1 | |
| SCHEMBL25303449 | 0.73 | NPBWR1 (0.35) | MAPTALDH1A1IDO1MEN1KMT2A | |
| SCHEMBL8612212 | 0.72 | MC4R (0.37) | MAPTALDH1A1IDO1CYP3A4CYP1A2 | |
| SCHEMBL3746249 | 0.69 | FFAR1 (0.50) | MAPTFFAR1FFAR4ALDH1A1NPSR1 | |
| SCHEMBL12127343 | 0.68 | ALDH1A1 (0.50) | ALDH1A1NPSR1MEN1KMT2AUSP2 | |
| SCHEMBL1560923 | 0.66 | CYP3A4 (0.45) | MAPTALDH1A1IDO1MEN1KMT2A | |
| SCHEMBL8540496 | 0.65 | MC4R (0.39) | GRK2IDO1 | |
| SCHEMBL444271 | 0.64 | RPA1 (0.48) | MAPTALPLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10537631 | 0.64 | IDO1 (0.43) | MAPTALDH1A1NPSR1IDO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022584-A1 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2002-03-21 | — | — | WO | disclosed |