SCHEMBL30089883

SCHEMBL30089883

Clc1ccc(-c2nc[nH]n2)c(Cl)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AHR P35869 1/20 0.41
ALPL P05186 5/20 0.41
HSD11B1 P28845 1/20 0.41
DPP4 P27487 1/20 0.40
DPP8 Q6V1X1 1/20 0.40
MAPT P10636 3/20 0.40
HPGD P15428 1/20 0.40
KMT2A Q03164 2/20 0.39
MEN1 O00255 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
KDM4E B2RXH2 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
EGLN2 Q96KS0 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HSP90AB1 P08238 1/20 0.38
MGAM O43451 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
SI P14410 1/20 0.38
RAB9A P51151 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16181369 0.82 RAB9A (0.40) ALPLHSD11B1MAPTHPGDKMT2A
SCHEMBL25303449 0.82 NPBWR1 (0.35) MAPTHPGDKMT2AMEN1SMN1; SMN2
SCHEMBL11206884 0.80 HSP90AA1 (0.46) MAPTHPGDKMT2AMEN1KDM4E
SCHEMBL6454308 0.79 IDO1 (0.57) MAPTHPGDKMT2AMEN1SMN1; SMN2
SCHEMBL10308885 0.78 LMNA (0.37) ALPLMAPTHPGDKMT2AMEN1
SCHEMBL1528053 0.77 LDHA (0.52) ALPLHSD11B1HPGDKMT2ASMN1; SMN2
SCHEMBL12127343 0.76 ALDH1A1 (0.50) HPGDKMT2AMEN1SMN1; SMN2KDM4E
SCHEMBL7423922 0.76 MAPT (0.36) ALPLMAPTHPGDKMT2AMEN1
SCHEMBL11196684 0.75 SLC6A2 (0.42) KMT2A
SCHEMBL11198885 0.74 SLC6A2 (0.41) KMT2ASMN1; SMN2KDM4ETDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115677803-B Preparation method of glycoside derivative containing quinazoline structure and composition thereof and application of glycoside derivative and composition for preventing and treating kiwi fruit canker 贵州理工学院 2025-03-28 CN disclosed
CN-115521261-B Preparation method of mercapto-containing quinazolinone and composition thereof, and application of mercapto-containing quinazolinone in resisting kiwi fruit canker 贵州理工学院 2024-04-05 CN disclosed
CN-115521262-B Preparation method of quinazolinone containing phenyl and composition thereof, and application of quinazolinone and composition in resisting kiwi fruit canker 贵州理工学院 2024-04-05 CN disclosed
CN-115636795-B Preparation method of quinazolinone derivative containing thiobenzamide structure and composition thereof, and application of quinazolinone derivative and composition thereof in preventing and treating kiwi fruit canker 贵州理工学院 2024-04-05 CN disclosed
CN-117720495-A Preparation method of novel amide-containing coumarin derivative, antibacterial effect of composition and application of composition in aspect of promoting plant growth 贵州工业职业技术学院 2024-03-19 CN disclosed
CN-117720494-A Preparation method and application of novel coumarin derivative plant growth regulator and composition 贵州工业职业技术学院 2024-03-19 CN disclosed
CN-115636795-A Quinazolinone derivative containing thiobenzamide structure, composition and application of quinazolinone derivative in prevention and treatment of kiwifruit canker 贵州理工学院 2023-01-24 CN disclosed
CN-115521262-A Preparation method of phenyl-containing quinazolinone and composition thereof and application of phenyl-containing quinazolinone in resisting kiwifruit canker 贵州理工学院 2022-12-27 CN disclosed
CN-115521261-A Preparation method of sulfhydryl-containing quinazolinone and composition thereof and application of sulfhydryl-containing quinazolinone in resisting kiwifruit canker 贵州理工学院 2022-12-27 CN disclosed