Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 7/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.40 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.40 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.40 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.40 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.40 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.40 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.40 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.40 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.40 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
| ▸ | LONP1 | P36776 | 1/20 | 0.40 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.40 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.40 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.40 |
| ▸ | PSMA6 | P60900 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9740699 | 1.00 | REN (0.41) | RENCTSKPSMB11PSMA7PSMB1 | |
| SCHEMBL9740697 | 1.00 | REN (0.41) | RENCTSKPSMB11PSMA7PSMB1 | |
| SCHEMBL7279299 | 0.86 | ALOX12 (0.40) | CNR1CNR2GCK | |
| SCHEMBL7279293 | 0.86 | ALOX12 (0.40) | CNR1CNR2GCK | |
| Hydrochloric Acid SCHEMBL9741701 | 0.85 | ALOX12 (0.40) | CNR1CNR2GCK | |
| Hydrochloric Acid SCHEMBL9741705 | 0.85 | ALOX12 (0.40) | CNR1CNR2GCK | |
| SCHEMBL7424258 | 0.83 | CCR1 (0.40) | RENCTSKPSMB11PSMA7PSMB1 | |
| SCHEMBL7316693 | 0.82 | POLB (0.43) | CTSKCNR2GCK | |
| SCHEMBL7316703 | 0.82 | POLB (0.43) | CTSKCNR2GCK | |
| SCHEMBL9741069 | 0.82 | REN (0.47) | RENCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0337295-A2 | Renin-inhibiting N-heterocyclic dipeptides | E.R. Squibb & Sons, Inc. (US) | 1989-10-18 | — | — | EP | claimed |