Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | REN | P00797 | 16/20 | 0.46 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429221 | 0.83 | CTSK (0.52) | CTSLRENCTSBCTSSCTSK | |
| SCHEMBL7491645 | 0.83 | SYK (0.49) | CTSLRENHTRA1SYKCTSB | |
| SCHEMBL7329100 | 0.82 | CTSK (0.51) | CTSLRENCTSBCTSSCTSK | |
| SCHEMBL7434284 | 0.82 | CTSK (0.51) | CTSLRENCTSBCTSSCTSK | |
| SCHEMBL13256207 | 0.81 | REN (0.53) | CTSLRENSYKCTSBCTSS | |
| SCHEMBL8269721 | 0.81 | REN (0.53) | CTSLRENSYKCTSBCTSS | |
| SCHEMBL12631595 | 0.81 | REN (0.53) | CTSLRENSYKCTSBCTSS | |
| SCHEMBL7427885 | 0.80 | CTSB (0.49) | CTSLRENCTSBCTSSCTSK | |
| SCHEMBL7294910 | 0.79 | CTSK (0.53) | CTSLRENCTSBCTSSCTSK | |
| Acetone SCHEMBL7339838 | 0.79 | REN (0.59) | CTSLRENCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371179-A1 | Novel analogs of peptidase substrates | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-06 | — | — | EP | disclosed |
| EP-0368719-A2 | Novel analogs of peptidase substrates | MERRELL PHARMACEUTICALS INC. (US) | 1990-05-16 | — | — | EP | disclosed |