Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSL | P07711 | 4/20 | 0.51 |
| ▸ | CTSB | P07858 | 4/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | REN | P00797 | 6/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7329100 | 1.00 | CTSK (0.51) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7429221 | 0.93 | CTSK (0.52) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7278761 | 0.88 | REN (0.50) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7294910 | 0.87 | CTSK (0.53) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7276185 | 0.85 | CTSL (0.52) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7304744 | 0.85 | CTSB (0.49) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL10445293 | 0.84 | REN (0.46) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7427885 | 0.83 | CTSB (0.49) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL9011705 | 0.83 | REN (0.50) | CTSKCTSLCTSBCTSSREN | |
| SCHEMBL7427667 | 0.82 | REN (0.49) | CTSKCTSLCTSBCTSSREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0416393-A1 | Peptidyl difluorodiol renin inhibitors | ABBOTT LABORATORIES (US) | 1991-03-13 | — | — | EP | disclosed |