Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | CDC25B | P30305 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 7/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7412565 | 0.93 | HCAR3 (0.57) | HCAR3HTTCDC25BMAPTNPSR1 | |
| SCHEMBL7979477 | 0.83 | KMT2A (0.47) | HCAR3HTTMAPTPOLBKMT2A | |
| SCHEMBL7424106 | 0.80 | VCAM1 (0.48) | HTTMAPTMAPK1AKR1C1KMT2A | |
| SCHEMBL7410714 | 0.79 | HCAR3 (0.47) | HCAR3HTTCDC25BMAPTMAPK1 | |
| SCHEMBL7412123 | 0.79 | HSD11B1 (0.48) | HCAR3HTTCDC25BMAPTNPSR1 | |
| SCHEMBL7492678 | 0.77 | HCAR3 (0.53) | HCAR3HTTCDC25BMAPTNPSR1 | |
| SCHEMBL6583318 | 0.75 | TSHR (0.54) | MAPTMAPK1AKR1C1KMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL7412658 | 0.74 | HCAR3 (0.49) | HCAR3HTTCDC25BMAPTMAPK1 | |
| SCHEMBL8026140 | 0.73 | MEN1 (0.53) | HCAR3HTTCDC25BMAPTMAPK1 | |
| SCHEMBL5089045 | 0.72 | VCAM1 (0.51) | HTTMAPTMAPK1AKR1C1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |
| EP-1071669-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | Boehringer Ingelheim Pharma KG (DE) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999054313-A1 | BICYCLIC COMPOUNDS HAVING AN ANTI-THROMBITIC EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-10-28 | — | — | WO | disclosed |