Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7424865 | 0.83 | HCAR3 (0.53) | KMT2AMEN1CYP1A2TSHRCYP2C19 | |
| SCHEMBL7980982 | 0.81 | OPRM1 (0.45) | ALOX15OPRM1 | |
| SCHEMBL20703536 | 0.78 | MEN1 (0.47) | KMT2ALMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL7412565 | 0.77 | HCAR3 (0.57) | CYP3A4CYP2C19HCAR3HTTALDH1A1 | |
| SCHEMBL15494191 | 0.75 | MEN1 (0.47) | KMT2ALMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL3654176 | 0.74 | MEN1 (0.44) | KMT2ALMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL3660871 | 0.74 | MEN1 (0.44) | KMT2ALMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL12273135 | 0.74 | LMNA (0.68) | KMT2ALMNAMEN1CYP1A2CYP3A4 | |
| SCHEMBL7410714 | 0.74 | HCAR3 (0.47) | KMT2ALMNACYP1A2CYP2C19HCAR3 | |
| SCHEMBL7412123 | 0.74 | HSD11B1 (0.48) | KMT2ALMNAMEN1CYP1A2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6200976-B1 | FOR TREATING THROMBOSIS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-13 | — | — | US | disclosed |