Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7428941 | 0.82 | NPC1 (0.41) | ALDH1A1KMT2AHSD17B10MEN1HDAC1 | |
| SCHEMBL11083101 | 0.82 | ALDH1A1 (0.48) | ALDH1A1KMT2AHSD17B10MEN1TDP1 | |
| SCHEMBL5031610 | 0.78 | MMP2 (0.44) | KMT2AHSD17B10MEN1TDP1ELANE | |
| SCHEMBL29166106 | 0.78 | HDAC7 (0.53) | ALDH1A1KMT2AHSD17B10MEN1TDP1 | |
| SCHEMBL8968525 | 0.76 | HDAC1 (0.47) | ALDH1A1TDP1ELANEHDAC1HDAC7 | |
| SCHEMBL9191639 | 0.76 | HDAC1 (0.52) | ALDH1A1TDP1HDAC1HDAC7MAPT | |
| SCHEMBL7428845 | 0.75 | MMP2 (0.53) | MMP2MMP9 | |
| SCHEMBL8968521 | 0.74 | HDAC1 (0.51) | ALDH1A1TDP1HDAC1HDAC7MAPT | |
| Hydrochloric Acid SCHEMBL9394212 | 0.74 | HDAC1 (0.51) | ALDH1A1TDP1ELANEHDAC1HDAC7 | |
| SCHEMBL7430629 | 0.73 | TNF (0.54) | ALDH1A1HDAC1NPSR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053226-A1 | SULFONYLAMINO DERIVATIVES WHICH INHIBIT MATRIX-DEGRADING METALLOPROTEINASES | Novartis AG (CH) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999042443-A1 | SULFONYLAMINO DERIVATIVES WHICH INHIBIT MATRIX-DEGRADING METALLOPROTEINASES | NOVARTIS AG (CH) | 1999-08-26 | — | — | WO | disclosed |