Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9191639 | 0.85 | HDAC1 (0.52) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL9394212 | 0.84 | HDAC1 (0.51) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| SCHEMBL8968521 | 0.84 | HDAC1 (0.51) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| Hydrochloric Acid SCHEMBL7156167 | 0.79 | HDAC1 (0.56) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| SCHEMBL5031610 | 0.77 | MMP2 (0.44) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| SCHEMBL11878793 | 0.76 | MAOB (0.54) | — | |
| SCHEMBL29166106 | 0.76 | HDAC7 (0.53) | HDAC1HDAC7HDAC8HDAC3HDAC4 | |
| SCHEMBL11083101 | 0.76 | ALDH1A1 (0.48) | MMP2MMP9ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL7425111 | 0.76 | ALDH1A1 (0.42) | HDAC1HDAC7MMP2MMP9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL34474526 | 0.76 | TDP1 (0.46) | HDAC1HDAC7HDAC8HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699209-A1 | PROCESSES AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994026779-A1 | PROCESSES AND INTERMEDIATE COMPOUNDS USEFUL FOR THE PREPARATION OF PLATELET GLYCOPROTEIN IIb/IIIa INHIBITORS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1994-11-24 | — | — | WO | disclosed |