Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR132 | Q9UNW8 | 3/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 3/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421246 | 0.96 | GPR132 (0.44) | GPR132CTSLCTSBCTSDELANE | |
| SCHEMBL7417968 | 0.96 | GPR132 (0.44) | GPR132CTSLCTSBCTSDELANE | |
| SCHEMBL7421382 | 0.91 | REN (0.42) | GPR132CTSLCTSBCTSDELANE | |
| SCHEMBL7418157 | 0.90 | REN (0.45) | CTSDELANEITGB3ITGA2B | |
| SCHEMBL7415239 | 0.89 | REN (0.41) | GPR132CTSLCTSBCTSDELANE | |
| SCHEMBL8945566 | 0.89 | CTSD (0.47) | CTSBCTSDITGB3ITGA2BCTSS | |
| SCHEMBL7933938 | 0.89 | CTSD (0.47) | CTSBCTSDITGB3ITGA2BCTSS | |
| SCHEMBL7422064 | 0.88 | CTSD (0.47) | GPR132CTSDELANEACACBCYP3A4 | |
| SCHEMBL7421155 | 0.87 | CTSD (0.43) | CTSDITGB3ITGA2BCTSSCTSK | |
| SCHEMBL7422846 | 0.86 | CTSD (0.44) | CTSDITGB3ITGA2BCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773926-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1997-05-21 | — | — | EP | claimed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | claimed |
| WO-1996002499-A1 | DIFLUOROSTATONE ANTIVIRAL AGENTS | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-01 | — | — | WO | disclosed |