Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.35 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.32 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425475 | 0.79 | DRD2 (0.40) | DRD2DRD3LNPEPSLC1A3SLC1A2 | |
| SCHEMBL8397602 | 0.67 | MME (0.42) | SLC1A3SLC1A2SLC1A1OPRM1OPRD1 | |
| SCHEMBL5870039 | 0.67 | DRD2 (0.42) | DRD2DRD3LNPEPSLC1A3SLC1A2 | |
| SCHEMBL9372981 | 0.65 | ALOX5 (0.49) | DRD2DRD3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL5222079 | 0.63 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1TDP1ALDH1A1 | |
| SCHEMBL22775723 | 0.63 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1TDP1ALDH1A1 | |
| SCHEMBL5692348 | 0.63 | SLC1A3 (0.47) | SLC1A3SLC1A2SLC1A1TDP1ALDH1A1 | |
| SCHEMBL17152628 | 0.63 | AOC3 (0.49) | TAAR1 | |
| SCHEMBL30799628 | 0.63 | MME (0.52) | LTA4H | |
| SCHEMBL21548477 | 0.62 | SLC1A3 (0.56) | SLC1A3SLC1A2SLC1A1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941233-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022496-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-05-28 | — | — | WO | disclosed |