Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | DRD3 | P35462 | 2/20 | 0.40 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.35 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.35 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.34 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7425482 | 0.79 | DRD2 (0.38) | DRD2DRD3LNPEPOPRM1OPRD1 | |
| SCHEMBL27790946 | 0.70 | TAAR1 (0.48) | DRD2DRD3OPRM1OPRD1TAAR1 | |
| SCHEMBL5870039 | 0.68 | DRD2 (0.42) | DRD2DRD3LNPEPOPRM1OPRD1 | |
| SCHEMBL9372981 | 0.67 | ALOX5 (0.49) | DRD2DRD3TAAR1SLC1A3SLC1A2 | |
| SCHEMBL8397600 | 0.67 | TAS1R3 (0.40) | OPRM1OPRD1SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL934545 | 0.66 | MME (0.48) | OPRM1OPRD1TAAR1SLC1A3SLC1A2 | |
| SCHEMBL4461408 | 0.63 | OPRM1 (0.49) | DRD2DRD3OPRM1OPRD1TAAR1 | |
| SCHEMBL20809649 | 0.63 | OPRM1 (0.48) | DRD2DRD3LNPEPOPRM1OPRD1 | |
| SCHEMBL28128853 | 0.63 | DRD2 (0.51) | DRD2DRD3OPRM1OPRD1TAAR1 | |
| SCHEMBL2102408 | 0.62 | TAAR1 (0.55) | DRD2DRD3OPRM1OPRD1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0941233-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-15 | — | — | EP | disclosed |
| WO-1998022496-A2 | ANTIVIRAL PEPTIDE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1998-05-28 | — | — | WO | disclosed |