Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.42 |
| ▸ | CTSD | P07339 | 2/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.38 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30799628 | 0.80 | MME (0.52) | MME | |
| SCHEMBL8397600 | 0.79 | TAS1R3 (0.40) | MMECTSDTAS1R3TAS1R1CTSS | |
| SCHEMBL9572319 | 0.77 | SLC7A5 (0.42) | MMECTSDAAK1SLC1A3SLC1A2 | |
| SCHEMBL5692348 | 0.71 | SLC1A3 (0.47) | MMECTSSCTSKSLC1A3SLC1A2 | |
| SCHEMBL5222079 | 0.71 | SLC1A3 (0.47) | MMECTSSCTSKSLC1A3SLC1A2 | |
| SCHEMBL22775723 | 0.71 | SLC1A3 (0.47) | MMECTSSCTSKSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL6774341 | 0.70 | ALDH1A1 (0.47) | MMECTSSCTSKSLC1A3SLC1A2 | |
| Hydrochloric Acid SCHEMBL3995222 | 0.70 | ALDH1A1 (0.47) | MMECTSSCTSKSLC1A3SLC1A2 | |
| SCHEMBL8972083 | 0.70 | DPP7 (0.42) | CTSKSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL8398402 | 0.70 | SLC7A5 (0.36) | CTSDAAK1LARS1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5866684-A | Peptidyl inhibitors of viral proteases | HOFFMANN-LA ROCHE INC. (US) | 1999-02-02 | — | — | US | disclosed |