Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 3/20 | 0.67 |
| ▸ | CTSL | P07711 | 3/20 | 0.54 |
| ▸ | CTSS | P25774 | 2/20 | 0.54 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.54 |
| ▸ | ECE1 | P42892 | 3/20 | 0.53 |
| ▸ | MME | P08473 | 3/20 | 0.53 |
| ▸ | CASP3 | P42574 | 2/20 | 0.53 |
| ▸ | REN | P00797 | 2/20 | 0.53 |
| ▸ | CTSB | P07858 | 2/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA5A | P35218 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8769487 | 0.92 | CTSD (0.66) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL6132144 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL6446151 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL6446780 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL9740721 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL9232828 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL6449641 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL6445103 | 0.91 | CTSD (0.76) | CTSDCTSLCTSSTRPM8ECE1 | |
| SCHEMBL8769526 | 0.90 | CTSL (0.63) | CTSDCTSLCTSSTRPM8ECE1 | |
| Acetic Acid SCHEMBL7270658 | 0.88 | CTSD (0.73) | CTSDCTSLCTSSTRPM8ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993013066-A1 | CYCLIC AMIDES OF 3-AMINO-2-HYDROXY-CARBOXYLIC ACIDS AS HIV-PROTEASE INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1993-07-08 | — | — | WO | disclosed |