Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7422656 | 0.70 | DPP4 (0.34) | DPP4CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7416830 | 0.67 | — | — | |
| SCHEMBL8259967 | 0.66 | OPRM1 (0.43) | SLC6A2MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL3468959 | 0.66 | SLC6A2 (0.33) | SLC6A2MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL2986864 | 0.66 | ALDH1A1 (0.46) | MEN1KMT2ALMNA | |
| SCHEMBL2987797 | 0.64 | SLC6A2 (0.37) | SLC6A2MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL8185693 | 0.64 | SLC6A3 (0.39) | SLC6A2MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL14857042 | 0.63 | SLC6A2 (0.47) | SLC6A2MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL20505122 | 0.62 | SLC6A3 (0.37) | SLC6A2MEN1PRCPKMT2ASIGMAR1 | |
| SCHEMBL14856965 | 0.62 | SLC6A2 (0.50) | SLC6A2MEN1PRCPKMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5789415-A | Azacyclic-heterocyclic compounds as angiotension II receptor antagonists | PFIZER INC. (US) | 1998-08-04 | — | — | US | claimed |
| WO-1995002596-A1 | AZACYCLIC-HETEROCYCLIC COMPOUNDS AS ANGIOTENSIN II RECEPTOR ANTAGONISTS | PFIZER INC. (US) | 1995-01-26 | — | — | WO | claimed |