Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | PRCP | P42785 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8183498 | 0.79 | KCNA3 (0.33) | — | |
| SCHEMBL6595863 | 0.73 | SLC6A3 (0.50) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL6916553 | 0.73 | CHRM3 (0.48) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL6599116 | 0.71 | SLC6A3 (0.42) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL6597123 | 0.70 | SLC6A2 (0.41) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL4021039 | 0.70 | SLC6A3 (0.36) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL6595795 | 0.70 | SLC6A3 (0.40) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL18462027 | 0.69 | SLC6A3 (0.39) | SLC6A3LMNATSHRSLC6A2SLC6A4 | |
| SCHEMBL8189527 | 0.69 | LMNA (0.41) | LMNATSHRSLC6A2SLC6A4CHRM3 | |
| Gacyclidine SCHEMBL4465879 | 0.69 | SIGMAR1 (0.57) | SLC6A3SLC6A2SLC6A4MEN1PRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6107495-A | REACTING SPECIFIED 1-(2- OR 3-THIENYL) CYCLOHEXANES WITH A 1,5-DIHALOPENTANE TO FORM CYCLIC (THIENYLCYCLOHEXYL)AMINES SUCH AS 2-ALKYL-(3-THIENYL)CYCLOHEXYL PIPERIDINE; USE AS INTERMEDIATES TO RADIOACTIVE LABELLED MOLECULES | SOCIETE D'EXPANSION SCIENTIFIQUE EXPANSIA (FR) | 2000-08-22 | — | — | US | disclosed |