Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | F2RL3 | Q96RI0 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423973 | 0.84 | F2RL3 (0.42) | MAPTF2RL3ALDH1A1HPGDTSHR | |
| SCHEMBL7423959 | 0.80 | PDE4A (0.41) | MAPTALDH1A1CA12CA1CA2 | |
| SCHEMBL7422572 | 0.74 | CA12 (0.55) | MAPTALDH1A1PKMPOLBCA12 | |
| SCHEMBL829998 | 0.73 | CA12 (0.50) | MAPTF2RL3ALDH1A1GAAHPGD | |
| SCHEMBL16345751 | 0.72 | F2RL3 (0.46) | MAPTF2RL3ALDH1A1HPGDTSHR | |
| SCHEMBL5584574 | 0.71 | CA2 (0.53) | MAPTALDH1A1PKMHPGDTSHR | |
| SCHEMBL18317797 | 0.71 | ALDH1A1 (0.40) | MAPTF2RL3ALDH1A1PKMGAA | |
| SCHEMBL18317798 | 0.71 | ALPL (0.40) | MAPTF2RL3ALDH1A1HPGDTSHR | |
| SCHEMBL16345750 | 0.71 | F2RL3 (0.45) | MAPTF2RL3ALDH1A1HPGDTSHR | |
| SCHEMBL7428362 | 0.71 | ERN1 (0.44) | MAPTF2RL3ALDH1A1HPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054884-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | Darwin Discovery Limited (GB) | 2000-11-29 | — | — | EP | disclosed |
| US-6066657-A | Benzofuran-4-carboxamides and their therapeutic use | DARWIN DISCOVERY, LTD. (GB) | 2000-05-23 | — | — | US | disclosed |
| WO-1999040085-A1 | BENZOFURAN-4-CARBOXAMIDES AND THEIR THERAPEUTIC USE | DARWIN DISCOVERY LIMITED (GB) | 1999-08-12 | — | — | WO | disclosed |