SCHEMBL7426149 — predicted protein targets

Predicted protein targets (top 18)

	gene	UniProt	supporting neighbours	confidence
▸	MMP1	P03956	2/20	0.42

▸	MMP9	P14780	2/20	0.42

▸	MMP3	P08254	1/20	0.42

▸	ANPEP	P15144	1/20	0.40

▸	MAPK14	Q16539	1/20	0.37

▸	NTSR1	P30989	2/20	0.37

▸	PSEN1	P49768	2/20	0.36

▸	PSEN2	P49810	2/20	0.36

▸	APH1B	Q8WW43	2/20	0.36

▸	NCSTN	Q92542	2/20	0.36

▸	APH1A	Q96BI3	2/20	0.36

▸	PSENEN	Q9NZ42	2/20	0.36

▸	FOLH1	Q04609	1/20	0.35

▸	CTSL	P07711	1/20	0.35

▸	SLC6A3	Q01959	1/20	0.35

▸	CRHBP	P24387	1/20	0.34

▸	CRHR2	Q13324	1/20	0.34

▸	PPARG	P37231	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL7424540	0.89	MAPK1 (0.42)	NTSR1FOLH1
SCHEMBL7429682	0.84	NTSR1 (0.37)	MMP1MMP9MMP3MAPK14NTSR1
SCHEMBL5870191	0.82	MMP1 (0.48)	MMP1MMP9MMP3ANPEPNTSR1
SCHEMBL5870188	0.82	MMP1 (0.48)	MMP1MMP9MMP3ANPEPNTSR1
SCHEMBL5869703	0.82	MMP1 (0.48)	MMP1MMP9MMP3ANPEPNTSR1
SCHEMBL7426141	0.73	TAAR1 (0.38)	MMP1MMP9MMP3ANPEPSLC6A3
SCHEMBL5869912	0.71	MMP1 (0.47)	MMP1MMP9MMP3ANPEPNTSR1
SCHEMBL5869761	0.71	MMP1 (0.47)	MMP1MMP9MMP3ANPEPNTSR1
SCHEMBL5869767	0.71	MMP1 (0.47)	MMP1MMP9MMP3ANPEPNTSR1
SCHEMBL5869287	0.70	MAPK1 (0.44)	MMP1MMP9MMP3NTSR1FOLH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2002039997-A2	ACE-2 MODULATING COMPOUNDS AND USE THEREOF	MILLENNIUM PHARMACEUTICALS, INC. (US)	2002-05-23	—	—	WO	disclosed