Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 8/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7419827 | 0.94 | DRD2 (0.36) | ALDH1A1MAPTL3MBTL1TDP1GAA | |
| SCHEMBL7417314 | 0.93 | ALDH1A1 (0.43) | ALDH1A1MAPTL3MBTL1TDP1GAA | |
| SCHEMBL7423129 | 0.87 | ALDH1A1 (0.42) | ALDH1A1MAPTL3MBTL1TDP1GAA | |
| SCHEMBL7426296 | 0.80 | MAPT (0.49) | ALDH1A1MAPTL3MBTL1TDP1GAA | |
| SCHEMBL7534277 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4EKMT2A | |
| SCHEMBL7975648 | 0.75 | ALDH1A1 (0.32) | ALDH1A1TDP1KDM4EKMT2AMEN1 | |
| SCHEMBL7419832 | 0.73 | WDR5 (0.43) | ALDH1A1MAPTL3MBTL1GAANPSR1 | |
| SCHEMBL7417316 | 0.73 | ALDH1A1 (0.51) | ALDH1A1MAPTL3MBTL1KDM4ENPSR1 | |
| SCHEMBL7423123 | 0.71 | ALDH1A1 (0.55) | ALDH1A1MAPTL3MBTL1TDP1GAA | |
| SCHEMBL306012 | 0.66 | MEN1 (0.46) | ALDH1A1MAPTL3MBTL1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |