Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7423129 | 0.92 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL7417314 | 0.87 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7419827 | 0.79 | DRD2 (0.36) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7534271 | 0.78 | ALDH1A1 (0.57) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7423456 | 0.73 | ALDH1A1 (0.56) | ALDH1A1MEN1KMT2AKDM4EMAPT | |
| SCHEMBL3722707 | 0.71 | CTSB (0.53) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7423123 | 0.70 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ACYP1A2KDM4E | |
| SCHEMBL7975847 | 0.69 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2ACYP1A2MAPT | |
| SCHEMBL7422014 | 0.67 | SMN1; SMN2 (0.47) | ALDH1A1MEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7426078 | 0.66 | KDM4E (0.48) | ALDH1A1MEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946519-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998024771-A1 | BENZAMIDE DERIVATIVES HAVING A VASOPRESSIN ANTAGONISTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-06-11 | — | — | WO | disclosed |