SCHEMBL74264

SCHEMBL74264

C=CC(=O)Oc1ccc(C#Cc2ccc(CCCCC)cc2)cc1

nearest known ligand 0.84

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
THRB P10828 10/20 0.84
THRA P10827 8/20 0.56
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
ACACB O00763 5/20 0.45
ALDH1A1 P00352 2/20 0.44
FFAR1 O14842 1/20 0.44
FFAR4 Q5NUL3 1/20 0.44
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
CYP3A4 P08684 1/20 0.43
MAPK1 P28482 1/20 0.43
CASP1 P29466 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
SLCO1B3 Q9NPD5 1/20 0.43
SLCO1B1 Q9Y6L6 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14373513 0.99 THRB (0.82) THRBTHRAMEN1KMT2AACACB
SCHEMBL14373517 0.96 THRB (0.78) THRBTHRAMEN1KMT2AACACB
SCHEMBL74263 0.96 THRB (0.76) THRBTHRAMEN1KMT2AACACB
SCHEMBL14373507 0.93 THRB (0.72) THRBTHRAMEN1KMT2ALMNA
SCHEMBL11031162 0.92 THRB (1.00) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL74647 0.90 THRB (0.82) THRBTHRAKMT2AACACBALDH1A1
SCHEMBL10651481 0.90 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL6931228 0.90 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL4475071 0.90 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1
SCHEMBL2289080 0.90 THRB (0.97) THRBTHRAMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2371930-B1 A blue phase liquid crystal composition SONY CORP (JP) 2014-08-06 EP claimed
US-12032193-B2 Optical element and method for manufacturing the same AGC Inc. (JP) 2024-07-09 US disclosed
US-20230339238-A1 IMAGE RECORDING METHOD AND INK JET-RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
US-20230339238-A1 IMAGE RECORDING METHOD AND INK JET-RECORDED MATERIAL FUJIFILM CORPORATION (JP) 2023-10-26 US disclosed
US-20230176270-A1 OPTICAL ELEMENT AND METHOD FOR MANUFACTURING THE SAME AGC Inc. (JP) 2023-06-08 US disclosed
US-20230168543-A1 OPTICAL ELEMENT AGC Inc. (JP) 2023-06-01 US disclosed
US-20220169880-A1 IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2022-06-02 US disclosed
US-20210403742-A1 INK SET FOR INKJET RECORDING AND IMAGE RECORDING METHOD FUJIFILM CORPORATION (JP) 2021-12-30 US disclosed
EP-3778248-A1 IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2021-02-17 EP disclosed
US-20210008916-A1 IMAGE FORMING METHOD FUJIFILM CORPORATION (JP) 2021-01-14 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed
US-20070170394-A1 Polymerizable liquid crystal composition and optically anisotropic medium DAINIPPON INK AND CHEMICALS, INC. (JP) 2007-07-26 US disclosed
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof CHISSO CORPORATION 2007-06-14 US disclosed
US-20070126966-A1 Base film for liquid-crystal panel, functional film for liquid-crystal panel, manufacturing process for functional film and manufacturing apparatus for functional film DAI NIPPON PRINTING CO., LTD. (JP) 2007-06-07 US disclosed
EP-1770415-A1 CONDENSER FILM, LIQUID CRYSTAL PANEL, BACKLIGHT AND METHOD FOR PRODUCING CONDENSER FILM Kuraray Co., Ltd., Kurashiki Plant (JP) 2007-04-04 EP disclosed
US-20070047421-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047419-A1 Optical recording method, optical recording apparatus, optical recording medium, and optical reproducing method FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070042275-A1 Composition for optical recording, optical recording medium, and production method thereof FUJI PHOTO FILM CO., LTD. 2007-02-22 US disclosed
EP-1754768-A1 POLYMERIZABLE LIQUID CRYSTAL COMPOSITION AND OPTICALLY ANISOTROPIC BODY Dainippon Ink and Chemicals, Incorporated (JP) 2007-02-21 EP disclosed
US-20070026165-A1 Liquid crystal display and manufacturing method of same DAI NIPPON PRINTING CO., LTD. (JP) 2007-02-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070134447-A1 Lateral a-substituted acrylate compound and polymer thereof AFF1, CNKSR1, LEF1 THRB 3134/4885THRA 1793/4885MEN1 531/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.