SCHEMBL742653

SCHEMBL742653

O=P(O)(O)OC[C@H]1O[C@H](O)[C@@H](O)[C@@H](O)[C@@H]1O

nearest known ligand 0.78

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 2/20 0.78
▸ AMDHD2 Q9Y303 1/20 0.62
▸ IGF2R P11717 4/20 0.58
▸ P2RY14 Q15391 4/20 0.44
▸ UMPS P11172 2/20 0.43
▸ ATIC P31939 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4323207 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL15628068 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL977102 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL9117406 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL345396 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL12377166 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL799813 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL48379 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL21926734 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS
SCHEMBL22107998 1.00 FBP1 (0.78) FBP1AMDHD2IGF2RP2RY14UMPS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 934 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3620510-B2 FERMENTATIVE PRODUCTION OF OLIGOSACCHARIDES BY TOTAL FERMENTATION UTILIZING A MIXED FEEDSTOCK CHR HANSEN HMO GMBH (DE) 2026-05-27 — — EP claimed
US-12636363-B2 Anti-transferrin receptor fusion proteins and methods of use thereof DENALI THERAPEUTICS INC. (US) 2026-05-26 — — US claimed
CN-122060031-A Alpha 2 delta 1 targeted degradation molecule alpha 2 delta 1-LYTAC, derivative thereof and application 暨南大学 2026-05-19 — — CN claimed
US-12622952-B2 Formulations comprising recombinant acid α-glucosidase AMICUS THERAPEUTICS, INC. (US) 2026-05-12 — — US claimed
WO-2026090085-A1 TREATMENT OF CD33 RELATED DISEASES AND DISORDERS EMPIRICO INC. (US) 2026-04-30 — — WO claimed
EP-3187508-B1 LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF BIOMARIN PHARM INC (US) 2026-04-22 — — EP claimed
US-20260077025-A1 SIALYLATED GLYCOPROTEIN COMPOSITION AND USES THEREOF ULTRAGENYX PHARMACEUTICAL INC (US) 2026-03-19 — — US claimed
EP-3924473-B1 ENZYMATIC PRODUCTION OF MANNOSE BONUMOSE INC (US) 2026-01-28 — — EP claimed
US-20250387477-A1 ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF DENALI THERAPEUTICS INC. (US) 2025-12-25 — — US claimed
US-20250367284-A1 ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF DENALI THERAPEUTICS INC. (US) 2025-12-04 — — US claimed
US-11357834-B2 Recombinant α-galactosidase A for treatment of Fabry disease AMICUS THERAPEUTICS, INC. (US) 2022-06-14 — — US claimed
US-20220162578-A1 HIGHLY POTENT ACID ALPHA-GLUCOSIDASE WITH ENHANCED CARBOHYDRATES WILMINGTON TRUST, NATIONAL ASSOCIATION 2022-05-26 — — US claimed
EP-3997214-A1 CHEMICALLY-MODIFIED ADENO-ASSOCIATED VIRUS Centre national de la recherche scientifique (FR) 2022-05-18 — — EP claimed
US-20220127591-A1 LYSOSOMAL ENZYMES MODIFIED BY CELL BASED GLYCOENGINEERING GLYCODISPLAY APS (DK) 2022-04-28 — — US claimed
US-20220127653-A1 ENZYMATIC PRODUCTION OF MANNOSE X-CALIBER RURAL CAPITAL, LLC 2022-04-28 — — US claimed
CN-109475607-B Formulations comprising recombinant acid alpha-glucosidase 阿米库斯治疗学公司 2022-04-26 — — CN claimed
US-20220119547-A1 SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES GENZYME CORPORATION 2022-04-21 — — US claimed
EP-3436053-B1 FORMULATIONS COMPRISING RECOMBINANT ACID ALPHA-GLUCOSIDASE AMICUS THERAPEUTICS INC (US) 2022-04-06 — — EP claimed
EP-3946243-A1 ANTI-AGING COSMETIC COMPOSITION Givaudan SA (CH) 2022-02-09 — — EP claimed
EP-1883394-B1 LIPID CONSTRUCT FOR DELIVERY OF INSULIN TO A MAMMAL SDG INC (US) 2018-03-28 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12636363-B2 Anti-transferrin receptor fusion proteins and methods of use thereof IDUA, TFRC, TPST2 FBP1 432/4885AMDHD2 1224/4885IGF2R 34/4885
US-12622952-B2 Formulations comprising recombinant acid α-glucosidase MAN2B1, MAN2A1, MANBA FBP1 134/4885AMDHD2 218/4885IGF2R 53/4885
US-20220119547-A1 SITE-SPECIFIC GLYCOENGINEERING OF TARGETING MOIETIES CD2BP2, CD74, ENGASE FBP1 1501/4885AMDHD2 914/4885IGF2R 115/4885
US-20250387477-A1 ANTI-TRANSFERRIN RECEPTOR FUSION PROTEINS AND METHODS OF USE THEREOF TFRC, IDUA, TPST2 FBP1 560/4885AMDHD2 1150/4885IGF2R 35/4885
US-20260077025-A1 SIALYLATED GLYCOPROTEIN COMPOSITION AND USES THEREOF M6PR, NEU2, NEU4 FBP1 566/4885AMDHD2 368/4885IGF2R 26/4885
US-11357834-B2 Recombinant α-galactosidase A for treatment of Fabry disease GLA, GAA, GBA1 FBP1 416/4885AMDHD2 109/4885IGF2R 1489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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