Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 1/20 | 0.54 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.54 |
| ▸ | NAMPT | P43490 | 6/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9081976 | 0.84 | TERT (0.53) | TERTTBXAS1NAMPTFPR2SMN1; SMN2 | |
| SCHEMBL6451096 | 0.81 | FPR2 (0.55) | TERTTBXAS1TAAR1FPR2GAA | |
| SCHEMBL17470979 | 0.81 | SMN1; SMN2 (0.52) | TERTTBXAS1NAMPTTAAR1FPR2 | |
| Treamid SCHEMBL17483104 | 0.81 | TBXAS1 (0.54) | TERTTBXAS1NAMPTFPR2GAA | |
| SCHEMBL17383408 | 0.81 | GAA (0.58) | NAMPTGAASMN1; SMN2KDM4EHTT | |
| SCHEMBL13034815 | 0.80 | TERT (0.49) | TERTTBXAS1NAMPTFPR2 | |
| SCHEMBL7198930 | 0.80 | TERT (0.49) | TERTTBXAS1NAMPTFPR2GAA | |
| SCHEMBL434372 | 0.80 | TERT (0.49) | TERTTBXAS1NAMPTTAAR1FPR2 | |
| SCHEMBL16133628 | 0.80 | TERT (0.49) | TERTTBXAS1NAMPTFPR2FDPS | |
| SCHEMBL18381303 | 0.80 | TBXAS1 (0.64) | TERTTBXAS1NAMPTGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1223933-A2 | 5-MEMBERED HETEROCYCLE DERIVATIVES, PRODUCTION THEREOF AND USE THEREOF AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2002-07-24 | — | — | EP | claimed |
| WO-2001026656-A2 | 5-MEMBERED HETEROCYCLE DERIVATIVES AND USE THEREOF AS MONOAMINE OXIDASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.) (FR) | 2001-04-19 | — | — | WO | claimed |